Published: 2025-05-09
Pharmacy and Medicine
Isolation and selection of bacteria producing inhibitors of Staphylococcus aureus and Cutibacterium acnes from human skin microbiome

Searching for antibacterial agents to provide new antibiotics was continuously researched. The most common source of natural antibacteriala agents was bacteria. The bacteria can be isolated from soil, water, plants, animals and the human. The aim of this study was to select bacteria from the skin microbiome that have the ability to inhibit S. aureus and C. acnes. The experimental research methods were used such as agar well diffusion method and agar spot test. Five of skin microorganisms with the ability to inhibit bacteria were selected from 72 of the human skin microbiome with a rate of 6.9%. Bacillus velezesis 48 isolated from the skin microflora of people without dermatological diseases aged 18-25 years. This strain had the ability to produce antibacterias substances. Bacillus velezesis 48 inhibits S. aureus and C. acnes with determined sterile diameters of 3.3±0.3 mm and 30.6±0.6 mm, respectively. The antibacterial substance extracted with diethyl ether solvent in BHI medium inhibited S. aureus with a sterile diameter of 8 ±0.3 mm and C. acnes of 14±0.3 mm. This antibacterial substance needs to determine its chemical structure, physical and chemical properties. This antibacterial substance can provid addition antibiotics against S. aureus and C. acnes that cause skin infections.
The use of intravenous Quinolone antibiotics at the clinical departments of Can Tho General Hospital

The safe and appropriate use of quinolones is an important factor in reducing bacterial resistance. To survey some patient characteristics, indications, dosage, and the possibility of switching from intravenous to oral administration in patients using intravenous Quinolone in clinical departments of Can Tho General Hospital. All inpatients using intravenous Quinolone antibiotics in clinical departments of Can Tho City General Hospital from 15/2/2022 to 30/4/2022. Evaluation criteria according to the Ministry of Health's 2020 Guidelines for the Management of Antibiotic Use in Hospitals, dosage will be based on the instruction of each drug. Among 190 patients, the average age of the patient group was 64.12 ± 16.3 years. The male-to-female ratio is 1:1.53. Ciprofloxacin was prescribed the most (53.2% of all medical records). Dosage of ofloxacin 800 mg/24 hours, is to be reconsidered. There are 0.9%, 4.6%, and 2.8% respectively of ofloxacin, levofloxacin, and ciprofloxacin whose dose has not been adjusted appropriately. Patients who have their route of administration converted from intravenous to oral are 5.8%. Compliance with recommended doses and dose adjustment in patients with impaired renal function should be noted. Switching the way of administration should be considered to reduce costs but maintain treatment effectiveness.
Evaluation of genetic characteristics of Eclipta Prostrata in the Mekong Delta based on morphological characteristics and molecular markers of ITS

False daisies, a medicinal plant, can adapt well to natural conditions and they often grow wild in many places. This plant has many benefits for human health because it contains many valuable medicinal ingredients and can be applied in the treatment of liver diseases, internal bleeding, dermatitis, eye pain, and other illnesses. The study aims to evaluate the agronomic characteristics of Eclipta prostrata samples in seven provinces in the Mekong Delta based on morphology and combined molecular biology methods to determine genetic relationships. Initial results revealed the genetic characteristics of Eclipta prostrata samples which show a certain diversity in stem length, leaf width, and root length. Through ITS region sequence analysis, it was determined that seven Eclipta prostrata samples all belong to the species Eclipta prostrata. Thereby, the research results can be applied to germplasm resource conservation and molecular identification of medicinal plants.
A study on the antifatigue effect of ethanol extract from Sam dat Con Dao root (Parietaria Debilis G. Forst. Urticaceae)

Sam dat Con Dao (Parietaria debilis G.Forst. Urticaceae), a native species in Con Dao, has been traditionally used by people to enhance health. However, there is currently no scientific research evaluating the herb's anti-fatigue effects; This study aims to investigate the antifatigue effect of ethanol extract from Sam dat Con Dao roots. To evaluate the anti-fatigue effects of the ethanol extract on male mice, an exhausted swimming mouse model was used. Assess the swimming time of the test batches in comparison to the control batch at the milestones of 60 minutes, 7 days, and 14 days after administering the extract. Results indicated that the absolute and relative swimming times of groups of mice using the extract at doses of 0.25 g/kg and 0.49 g/kg did not increase compared to the control group after 60 minutes. However, after 7 days and 14 days, they showed a statistically significant increase compared to the control group at the same time. Therefore, the ethanol extract of Sam dat Con Dao roots at both doses of 0.25 g/kg and 0.49 g/kg exhibits long-term anti-fatigue effects
Engineering and Technology
Methods for producing absolute alcohol

Absolute alcohol (also known as dry alcohol) is a widely used material in many national economic sectors. The dry alcohol production industry is growing aggressively around the world. It is associated with the chemical, food, medicine, agriculture and electronics industries. Dry alcohol can be used to produce synthetic rubber, rayon, and serve as an organic solvent in the plastics, textiles, and cosmetics industries. There are many methods of producing absolute alcohol. Regardless of the method, the product produced must achieve the quality of being an absolute alcohol, that is, 100% Ethanol. This article introduces a new production method - the Combined Chemical-Physical method. The outcome of this method is a product quality that achieves the established goals.
Social Sciences and Humanities
Some challenges regarding joint liability for non - contractual damages. Current situation and solutions

Joint liability for compensation for non-contractual damages is an important legislation enacted by the 2015 Civil Code, in order to protect life, welfare, and honor, and promote justice, labor rights and interests. It also protects the legitimate interests of individuals, their honor and reputation, and the property of legal persons or other entities when violated. Although it has been given attention and specifically stipulated in legal documents, when put into practice, there are many inadequacies and problems. Not only does it lead to difficulties for competent state agencies in charge of adjudication, but it also allows the legitimate rights and interests of the injured party not to be completely and comprehensively recognized and protected. Within the scope of this article, the author will analyze the contributing problems and limitations and propose solutions to address the inadequacies of joint liability for compensation for non-contractual damages in the prevailing system.
Solutions to enhance the efficiency of resolving credit contract disputes at the appellate stage: a perspective from the Can Tho people's Court

This study examines the increasing number of complex credit contract disputes in Can Tho City and the challenges in resolving them. The research highlights issues such as legal inadequacies, the lack of coordination between agencies, and the resulting impact on public trust in the judiciary. It aims to provide solutions to enhance the efficiency of dispute resolution at the appeal stage. The study was carried out by analyzing data from 2015 to 2022 and offers insights into improving the legal framework and interagency cooperation. Ultimately, the research contributes to enhanced protection of the rights of individuals involved in credit contract disputes.
Natural Sciences
Hausdorff continuity of weak efficiency mapping for parametric set optimization problems

The objective was to study the continuity of the efficient solution maps of perturbed set optimization problems in normed spaces. The semicontinuous, continuous concepts and concepts related to the convexity of a set-valued map such as segmented ?-convexity, naturally segmented ?-quasiconvexity, arcwise connected ?-convexity, naturally arcwise connected ?-quasiconvexity were reviewed. Next, we consider generalized scalarization functions of Gerterwitz function and their properties, in which in which the continuity played an important role in our analysis. Based on the properties of the above scalarization functions, a scalar representations of the weakly efficient solution for the set optimization problem is built. Finally, employing properties of the nonlinear scalarization function with the compactness of constraining set and the ?-continuity as well as naturally arcwise connected ?-quasiconvexity assumptions on the objective map, we established sufficient conditions for continuity of the efficient solution maps to problems
Agriculture and Environment
Application of GIS and remote sensing to analyze agricultural land use changes in Can Tho city from 2010 to 2023

The objective of this study was to analyze the fluctuations in agricultural land use in Can Tho City from 2010 to 2023 using GIS and remote sensing technology. The study applied object-oriented classification methods on Landsat images and unsupervised classification on multi-temporal MODIS images to create a map of the current agricultural land use in Can Tho City. The overall accuracy for the years 2010 and 2023 was 87.4% and 82.3%, respectively, with kappa coefficients of 0.77 and 0.87. The classification results identified seven types of land use: triple rice cropped, double rice cropped, annual crops, perennial crops, aquaculture, built-up areas, and rivers. Additionally, the study identified 38 instances of agricultural land use changes, accounting for 50.21% of the total area, with the most significant changes being from double rice to triple rice cropped, from triple rice to annual crops, and from triple rice to perennial crops. Our results can provide information on agricultural land use change trends, supporting effective agricultural land management and planning for the locality.